EFFERVESCENT FLOATING TABLETS OF CIPROFLOXACIN HYDROCHLORIDE: FORMULATION AND IN VITRO EVALUATION

Abstract

Ciprofloxacin hydrochloride is a broad spectrum antibiotic used to treat various  bacterial infections. However, its short half-life and the need for frequent dosing can limit its therapeutic effectiveness. Effervescent floating tablets offer a promising solution by providing controlled drug release and prolonged gastric retention, thus improving bioavailability and patient compliance. This study focuses on the formulation and in vitro evaluation of effervescent floating tablets of ciprofloxacin hydrochloride.