INVESTIGATION OF CO-SOLVENTS' IMPACT ON THE SOLUBILITY OF FUROSEMIDE

Abstract

Background: The low water solubility of furosemide, a popular loop diuretic, restricts its bioavailability and therapeutic effectiveness. Improving furosemide's solubility is essential to increasing its efficacy and absorption. Co-solvents can improve the solubility of medications like furosemide that are not very soluble in water when combined with water.